Endocrine Abstracts

Introduction: Pituitary metastases are rare complications of malignancy, representing only 1% of surgical tumours of the pituitary gland. They are usually encountered in elderly patients with disseminated malignant disease. The most frequent are metastases of breast and lung cancer. In this report, we describe a rare case of a metastatic breast cancer to the pituitary gland.Observation: A 32-year-old female presented with blurred vision and diminished vi...

Introduction: Papillary thyroid carcinomas (PTC) represent up to 87% of all thyroid cancers with an incidence that has doubled over the past 30 years. Hashimoto’s thyroiditis (HT) and Graves’ disease are two autoimmune thyroid diseases representing the most common causes of hypothyroidism and hyperthyroidism, respectively. Although PTC with coexisting HT has been reported in literature, its association with GD is not a common condition. Herein, we report three cases ...

Introduction: Retrospective analysis has shown that approximately 17–84% of patients suffering from primary hyperparathyroidism have a concomitant thyroid disease. However, it still remains controversial whether these two pathologies happen coincidental or are caused by specific risk factors or genetic changes. In this study we aimed to evaluate concurrently detected thyroid pathologies in patients who underwent surgery for primary hyperparathyroidism.<p class="abstex...

Introduction: Ganglioneuromas (GN) are rare benign tumors arising from the neural crest tissue and are most commonly located in the posterior mediastinum and retroperitoneum; they are rarely found in the adrenal gland. We report a case of a female patient with adrenal ganglioneuroma.Observation: A 51-year-old female patient with no previous comorbidities was admitted to our hospital. She had no significant past medical or surgical history. She had sympto...

Introduction: Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, characterized by chronic anovulation and hyperandrogenism. Hirsutism, defined as excessive terminal hair that appears in a male pattern in a woman, is frequently present in patients with PCOS. We aimed to determine the clinical and biological characteristics of hirsute patients with PCOS.Methods: It was a retrospective study included 30 women diagnosed with PCOS according to the ...

Introduction: The reactive pituitary gland enlargement is a non-neoplastic growth of at least one pituitary lineage, which can often be essential or secondary to prolonged deficit of a gland target. It may be difficult to differentiate from functional pituitary adenomas. Herein we report a case of pituitary hyperplasia secondary to congenital primary hypothyroidism diagnosed at the age of 38 years.Observation: A 38-year-old female patient presented with ...

Introduction: Myasthenia gravis is an autoimmune neuromuscular disease characterized by the presence of anti-acetylcholine receptor antibodies. It can be isolated or associated with other auto-immune conditions. Graves’ disease is an autoimmune disorder typically characterized by the presence of circulating autoantibodies that tie to and stimulate the thyroid hormone receptor. Coexisting myasthenia gravis and Graves’ disease is a rare but well recognized condition. T...

IntroductionPhaeochromocytomas are rare neuroendocrine tumors secreting high levels of catecholamines, able to exert serious metabolic and cardiovascular effects. Glucose intolerance are common complications that require an early recognition and treatment.MethodsA retrospective study was conducted to assess the prevalence of metabolic and cardiovascular complications in 35 patients diagnosed with pheochromocy...

The term adrenal ’incidentaloma’ is referring to an adrenal mass discovered incidentally during an abdominal imaging exam not motivated by the exploration of an adrenal pathology. The prevalence of diabetes in incidentaloma is high therefore a cortisol secretion should be searched. This is a retrospective study conducted on 100 patients with adrenal incidentaloma. These patients are divided into two groups; the first group is made up of diabetics (G1: n = 31...

ObjectiveDescribe the clinical, paraclinical, etiological and therapeutic profile of adrenal incidentalomas.Material and methodsRetrospective study, conducted on 100 patients previously hospitalized in the endocrinology department of the university hospital center RABTA, following the fortuitous discovery of an adrenal mass over a period of 10 years.ResultsThe mea...